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Symptoms that signal thumb arthritis include pain with thumb joint in osteoarthritis that involve gripping or pinching, swelling and tenderness at the base of the thumb, and an aching discomfort after prolonged use. What are the symptoms of hand arthritis? Submit a Comment Cancel reply Your email address will not be published. Hard plastic splints, either custom-made or off the shelf, also may help increase function and decrease pain. There are several types of thumb joint in osteoarthritis that can affect your hands.